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ONCOLOGY RESEARCH
TABLES OF CONTENTS
Volume 12, Numbers 1-12
VOLUME 12, NUMBERS 11/12
Commentary
Wilms' Tumor: A Paradigm for
the New Genetics
Karim Malik, Pearlly Yan, Tim H.-M. Huang, and Keith W. Brown
Short Communication
Novel mdm2 Splice Variants
Identified in Pediatric Rhabdomyosarcoma Tumors and Cell Lines
Frank Bartel, Alan C. Taylor, Helge Taubert, and Linda C. Harris
Laboratory Research
Mutation and Functional Analysis
of IL-13 Receptors in Human Malignant Glioma Cells
Mariko Kawakami, Pamela Leland, Koji Kawakami, and Raj K. Puri
Involvement of Claudin-1 in
the b-Catenin/Tcf Signaling Pathway and its
Frequent Upregulation in Human Colorectal Cancers
Nobutomo Miwa, Mikio Furuse, Shoichiro Tsukita, Norio Niikawa, Yusuke
Nakamura, and Yoichi Furukawa
Antitumor Activity of ER-51785,
a New Peptidomimetic Inhibitor of Farnesyl Transferase: Synergistic Effect
in Combination With Paclitaxel
Katsuji Nakamura, Atsumi Yamaguchi, Masayuki Namiki, Hiroshi Ishihara,
Takeshi Nagasu, James J. Kowalczyk, Ana Maria Garcia, Michael D. Lewis,
and Kentaro Yoshimatsu
Antisense of ATP Synthase Subunit
e Inhibits the Growth of Human Hepatocellular Carcinoma Cells
Hao Ying, Yanlin Yu, and Yonghua Xu
Molecular Characterization
of the DICE1 (DDX26) Tumor Suppressor Gene in Lung Carcinoma Cells
Ilse Wieland, Albrecht Röpke, Markus Stumm, Christian Sell,
Ulrich H. Weidle, and Peter F. Wieacker
Antitumor Effect of VNP20009,
an Attenuated Salmonella, in Murine Tumor Models
Xiang Luo, Zujin Li, Stanley Lin, Trung Le, Martina Ittensohn, David
Bermudes, Jacob D. Runyab, Shu-ying Shen, Jianping Chen, Ivan C. King,
and Li-mou Zheng
Volume 12 Subject and Author Index
VOLUME 12, NUMBER 9/10
LABORATORY RESEARCH
Antagonistic Effect of the Combination
Gemcitabine/Topotecan in Ovarian Cancer Cells
Mariagrazia Distefano, Cristiano Ferlini, Rosa De Vincenzo, Cristiana
Gaggini, Salvatore Mancuso, and Giovanni Scambia
Cytotoxicity, DNA Damage, and
Cell Cycle Perturbations Induced by Two Representative Gold(III) Complexes
in Human Leukemic Cells With Different Cisplatin Sensitivity
Marcella Coronnello, Giordana Marcon, Stefania Carotti, Barbara
Caciagli, Enrico Mini, Teresita Mazzei, Pierluigi Orioli, and Luigi Messori
Cell-Cell Adhesion-Independent
Killing Due to Lymphokine-Activated Killer Cells Against Glioblastoma Cell
Lines
Fumio Komatsu and Tomoko Masuda
Prostaglandin A1 Inhibits
Stress-Induced NF-kB Activation and Reverses
Resistance to Topoisomerase II Inhibitors
Yoonkyung C. Boller, Lori M. Brandes, Rosalind L. Russell, Z. Ping
Lin, Steven R. Patierno, and Katherine A. Kennedy
Induction of Apoptosis by Cidofovir
in Human Papillomavirus (HPV)-Positive Cells
Graciela Andrei, Robert Snoeck, Dominique Schols, and Erik De Clercq
Effects of Photodynamic Therapy
With Hypericin in Mice Bearing Highly Invasive Solid Tumors
Michael Blank, Gad Lavie, Mathilda Mandel, and Yona Keisari
Synergistic Effects of Clinically
Achievable Concentrations of 12-O-Tetradecanoylphorbol-13-acetate
in Combination With all-trans Retinoic Acid, 1a,25-Dihydroxyvitamin
D3, and Sodium Butyrate on Differentiation in HL-60 Cells
Xi Zheng, Richard L. Chang, Xiao-Xing Cui, Kathleen A. Kelly, Weichung
Joe Shih, Yong Lin, Roger Strair, Junghan Suh, Zheng Tao Han, Arnold Rabson,
and Allan H Conney
Growth Inhibitory Effects and
Radiosensitization Induced by Fatty Aromatic Acids on Human Cervical Cancer
Cells
Gabriella Ferrandina, Perla Filippini, Cristiano Ferlini, Nicola
Maggiano, Andrea B. Stoler, Erika Fruscella, Simona Mozzetti, Salvatore
Mancuso, Ralph S. Freedman, Giovanni Scambia, and Franco O. Ranelletti
VOLUME 12, NUMBER 8
LABORATORY RESEARCH
Characterization and Drug Sensitivity
of Four Newly Established Colon Adenocarcinoma Cell Lines to Antifolate
Inhibitors of Thymidylate Synthase
Giuseppe S. A. Longo, Julie Izzo, Richard Gorlick, Debabrata Banerjee,
Suresh C. Jhanwar, and Joseph R. Bertino
Selective Susceptibility of Transformed
T Lymphocytes to Induction of Apoptosis by PSC 833, an Inhibitor of P-Glycoprotein
Janeen Azare, Irene Pankova-Kholmyansky, Konstantin Salnikow, Dalia
Cohen, and Eliezer Flescher
4-[3-(2-Nitro-1-imidazolyl)propylamino]-7-chloroquinoline
Hydrochloride (NLCQ-1), a Novel Bioreductive Agent as Radiosensitizer In
Vitro and In Vivo: Comparison With Tirapazamine
Maria V. Papadopoulou, Ming Ji, Mira K. Rao, and William D. Bloomer
Demethylation by 5-aza-2´-deoxycytidine
(5-azadC) of p16INK4A Gene Results in Downregulation
of Vascular Endothelial Growth Factor Expression in Human Lung Cancer Cell
Lines
Keisuke Miki, Eiji Shimizu, Seiji Yano, Kenji Tani, and Saburo Sone
ATF3 Gene Regulates Cell Form
and Migration Potential of HT29 Colon Cancer Cells
Tatsuaki Ishiguro and Hirokazu Nagawa
Human Papilloma Virus 16 E7 Oncogene
Does Not Cooperate With RET/PTC 3 Oncogene in the Neoplastic Transformation
of Thyroid Cells in Transgenic Mice
Giuseppe Portella, Cristina Borselli, Massimo Santoro, Diego Gerbasio,
Maria Rosaria D'Armiento, Jacques E. Dumont, Catherine Ledent, Jay L. Rothstein,
Giancarlo Vecchio, and Alfredo Fusco
VOLUME 12, NUMBER 6/7
SPECIAL ABSTRACT ISSUE
A 2001 Millennium International Conference of Molecular and Tumor
Biology
"Stem Cell Differentiation, Genetic Reprogramming and Programmed
Cell Death"
Program and Abstracts
Nomikos Congress Center, Santorini, Greece
September 2-7, 2001
VOLUME 12, NUMBER 5, 2000
LABORATORY RESEARCH
Bone Metastasis Model With Multiorgan
Dissemination of Human Small-Cell Lung Cancer (SBC-5) Cells in Natural
Killer Cell-Depleted SCID Mice
Toyokazu Miki, Seiji Yano, Masaki Hanibuchi, and Saburo Sone
Indoloquinoxaline Compounds That
Selectively Antagonize P-Glycoprotein
Charles D. Smith, Cynthia B. Myers, Jack T. Zilfou, Staci N. Smith,
and David S. Lawrence
Differences in the Induction
of DNA Damage, Cell Cycle Arrest, and Cell Death by 5-Fluorouracil and
Antifolates
H. H. J. Backus, H. M. Pinedo, D. Wouters, C. M. Kuiper, G. Jansen,
C. J. van Groeningen, and G. J. Peters
CLINICAL RESEARCH
Angiogenic and Immune Parameters
During Recombinant Interferon-a2b Adjuvant Treatment
in Patients With Melanoma
Didier Dréau, Mareva Foster, Melanie Hogg, Jeanene Swiggett,
Walter D. Holder, and Richard L. White
VOLUME 12, NUMBER 4, 2000
LABORATORY RESEARCH
Induction of Hepatic Metallothioneins
in Tumor-Bearing IL-6-Null Mice
Andrei Molotkov, Masahiko Satoh, and Chiharu Tohyama
Human Interferon-g
Enhances Expression of Ganglioside GM2 on Human Lung Cancer Cells and Their
Susceptibility for Antiganglioside GM2 Monoclonal Antibody-Dependent Cellular
Cytotoxicity
Masaki Hanibuchi, Yasuhiko Nishioka, Hiroaki Yanagawa, Seiji Yano,
Prahlad Parajuli, Mika Bando, and Saburo Sone
Expression of the ATF3 Gene on
Cell Lines and Surgically Excised Specimens
Tatsuaki Ishiguro and Hirokazu Nagawa
4-[3-(2-Nitro-1-imidazolyl)propylamino]-7-chloroquinoline
Hydrochloride (NLCQ-1), a Novel Bioreductive Compound as a Hypoxia-Selective
Cytotoxin
Maria V. Papadopoulou, Ming Ji, Mira K. Rao, and William D. Bloomer
Sodium Butyrate-Induced Differentiation
of Human LIM2537 Colon Cancer Cells Decreases GSK-3b
Activity and Increases Levels of Both Membrane-Bound and APC/Axin/GSK-3b
Complex-Associated Pools of b-Catenin
Elizabeth Vincan, Christine S. F. Leet, Nancy I. Reyes, Rodney Dilley,
Robert J. S. Thomas, and Wayne A. Phillips
CLINICAL RESEARCH
Angiogenesis and p53 Expression
in the Colorectal Adenoma-Carcinoma Sequence
Stylianos A. Kakolyris, Loukas G. Kaklamanis, Michael J. Koukourakis,
Alexandra Giatromanolaki, Maria Rousomoustakaki, John C. Souglakos, Despina
K. Reppa, Vassilis A. Georgoulias, Kevin C. Gatter, and Adrian L. Harris
VOLUME 12, NUMBER 3, 2000
LABORATORY RESEARCH
Structure-Activity Studies of
Novobiocin Analogs as Modulators of the Cytotoxicity of Etoposide (VP-16)
Germana Rappa, Krishnamurthy Shyam, Aurelio Lorico, Øystein
Fodstad, and Alan C. Sartorelli
Induction of Hepatocellular Carcinoma
With High Metastatic Potential in WS/Shi Rats: Discovery of an Inbred Strain
Highly Susceptible to the Liver Carcinogen N-Nitrosomorpholine
Takashi Murai, Satoru Mori, Motoko Hosono, Yoshiko Iwakura, Akira
Takashima, Reiji Takeda, and Shoji Fukushima
Tumor Amplified Protein Expression
Therapy: Salmonella as a Tumor-Selective Protein Delivery Vector
Li-mou Zheng, Xiang Luo, Ming Feng, Zujin Li, Trung Le, Martina
Ittensohn, Mark Trailsmith, David Bermudes, Stanley L. Lin, and Ivan C.
King
Schedule-Dependent Interaction
Between Raltitrexed and 5-Fluorouracil in Human Colon Cancer Cell Lines
In Vitro
Yasuhiko Kano, Miyuki Akutsu, Kenichi Suzuki, Yasuo Yazawa, Saburo
Tsunoda, and Yusuke Furukawa
Radiation-Induced Cell Cycle
Delays and p53 Status of Early Passage Melanoma Cell Lines
Jayamala Parmar, Elaine S. Marshall, Geoffrey A. Charters, Karen
M. Holdaway, Andrew N. Shelling, and Bruce C. Baguley
Smad Protein Expression and Activation
in Transforming Growth Factor-b Refractory Human
Squamous Cell Carcinoma Cells
Wu Yan, Vincent F. Vellucci, and Michael Reiss
VOLUME 12, NUMBER 2, 2000
LABORATORY RESEARCH
Antitumor Activity of a-Galactosylceramide,
KRN7000, in Mice With the Melanoma B16 Hepatic Metastasis and Immunohistological
Study of Tumor Infiltrating Cells
Ryusuke Nakagawa, Isao Serizawa, Kazuhiro Motoki, Miyuki Sato, Hitomi
Ueno, Rieko Iijima, Hiromi Nakamura, Akihiro Shimosaka, and Yasuhiko Koezuka
Differential Gene Expression
of Hepatocellular Carcinoma Using cDNA Microarray Analysis
Wan-yee Lau, Paul B. S. Lai, Mun-fai Leung, Billy C. S. Leung, Nathalie
Wong, Gong Chen, Thomas W. T. Leung, and Choong-tsek Liew
Activation of PTHrP Gene Expression
in Squamous Carcinoma Cell Lines by Mutant Isoforms of the Tumor Suppressor
p53
John Foley, Connie S. King, Juan A. Jiménez, John J. Wysolmerski,
and William M. Philbrick
Apoptosis Cascade Proteins Are
Regulated In Vivo by High Intracolonic Butyrate Concentration: Correlation
With Colon Cancer Inhibition
Carmel Avivi-Green, Sylvie Polak-Charcon, Zecharia Madar, and Betty
Schwartz
Interleukin 8: An Autocrine Growth
Factor for Human Ovarian Cancer
Lei Xu and Isaiah J. Fidler
CLINICAL RESEARCH
Epidermal Growth Factor Receptor
Gene Amplification as a Prognostic Marker in Glioblastoma Multiforme: Results
of a Meta-Analysis
Michael Huncharek and Bruce Kupelnick
VOLUME 12, NUMBER 1, 2000
COMMENTARY
Molecular Polarity in Endothelial
Cells and Tumor-Induced Angiogenesis
Vincenzo Chiarugi, Marco Ruggiero, and Lucia Mangelli
LABORATORY RESEARCH
Mutational Alterations of the
p16CDKN2A Tumor Suppressor Gene Have Low Incidence in Mesenchymal
Chondrosarcoma
Dae Kyung Bae, Yong-Koo Park, Sung Gil Chi, Chun Woo Lee, and K.
Krishnan Unni
Coamplification of 3-Hydroxy-3-Methylglutaryl
Coenzyme A Reductase Genes in Methotrexate-Resistant Human Leukemia Cell
Lines
Srinivasan Srimatkandada, Shyam K. Dube, Mark Carmen, and Joseph
R. Bertino
CD18/CD54(+CD102, CD2/CD58 Pathway-Independent
Killing of Lymphokine-Activated Killer (LAK) Cells Against Glioblastoma
Cell Lines T98G and U373MG
Fumio Komatsu and Michiko Kajiwara
Inhibitory Effect of Liposomal
MDP-Lys on Lung Metastasis of Transplantable Osteosarcoma in Hamster
Yasuaki Nitta, Takashi Sugita, Yoshikazu Ikuta, and Teruo Murakami
CLINICAL RESEARCH
Angiogenic Interactions of Vascular
Endothelial Growth Factor, of Thymidine Phosphorylase, and of p53 Protein
Expression in Locally Advanced Gastric Cancer
A. Giatromanolaki, M. I. Koukourakis, G. P. Stathopoulos, A. Kapsoritakis,
G. Paspatis, S. Kakolyris, E. Sivridis, V. Georgoulias, A. L. Harris, and
K. C. Gatter
Expression of p53 and bcl-2 in
Clinically Localized Prostate Cancer Before and After Neo-Adjuvant Hormonal
Therapy
Anna M. Cesinaro, Mario Migaldi, Giovanni Ferrari, Giovanni Castagnetti,
Alberto Dotti, Carmela De Gaetani, Paolo Ferrari, and Gian P. Trentini