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ONCOLOGY RESEARCH
TABLES OF CONTENTS
Volume 11, Numbers 1-12, 1999
VOLUME 11, NUMBER 11/12, 1999
LABORATORY RESEARCH
Characterization of a Novel Immunocytolytic
Factor Secreted by Pancreatic Adenocarcinoma
Celia M. Divino, Luz P. Angel, Steven T. Brower, and Shu-Hsia Chen
Inhibition of Metastatic Carcinoma
Cell Growth in Livers by Poly(I):Poly(C)/Cationic Liposome Complex (LIC)
Kazuko Hirabayashi, Junichi Yano, Hisashi Takesue, Noriko Fujiwara,
and Tatsuro Irimura
Growth Inhibition and Antimetastatic
Effect of Antisense Poly-DNP-RNA on Human Breast Cancer Cells
Kun Ru, Shawn Schmitt, William I. James, and Jui H. Wang
Significant Increase of Adenovirus
Infectivity in Glioma Cell Lines by Extracellular Domain of hCAR
Toshiki Mori, Hirofumi Arakawa, Takashi Tokino, Katsuyoshi Mineura,
and Yusuke Nakamura
CLINICAL RESEARCH
P450 Expression in Brain Tumors
Heike Knüpfer, Matthias M. Knüpfer, Marc Hotfilder, and
Rainer Preiß
A Clinical-Pharmacological Evaluation
of Percutaneous Isolated Hepatic Infusion of Doxorubicin in Patients With
Unresectable Liver Tumors
Wen-Jen Hwu, Ronald R. Salem, Jeffrey Pollak, Melvin Rosenblatt,
Elizabeth D'Andrea, Janine J. Leffert, Susan Faraone, John C. Marsh, and
Guiseppe Pizzorno
Elevated Antibody Levels to Epstein-Barr
Virus Antigens in Patients With Hairy Cell Leukemia Compared to Controls
in Relation to Exposure to Pesticides, Organic Solvents, Animals, and Exhausts
Marie Nordström, Annika Linde, Lotti Schloss, Åsa Näsman,
and Lennart Hardell
Volume 11 Subject and Author Index
VOLUME 11, NUMBER 10, 1999
LABORATORY RESEARCH
Photokilling Mechanisms Induced by
Zinc(II)-Phthalocyanine on Cultured Tumor Cells
Angeles Villanueva, Verónica Domínguez, Silvia Polo,
Viíctor D. Vendrell, Cristina Sanz, Madealena Cañete, Angeles
Juarranz, and Juan C. Stockert
Cell Death in Paclitaxel-Dependent
Chinese Hamster Ovary Cells Is Initiated by the Loss of Telomeric DNA Repeats
Asha S. Multani, Joya Chandra, David J. McConkey, Subrata Sen, Fernando
Cabral, and Sen Pathak
Involvement of TNF-a
in Enhancement of Invasion and Metastasis of Colon 26-L5 Carcinoma Cells
in Mice by Social Isolation Stress
Wenjuan Wu, Takeshi Yamaura, Koji Murakami, Masaru Ogasawara, Kazuko
Hayashi, Jun Murata, and Ikuo Saiki
Cytotoxic Effects Toward Human Hematopoietic
Progenitor Cells and Tumor Cell Lines of Paclitaxel, Docetaxel, and Newly
Developed Analogues IDN5109, IDN5111, and IDN5127
Cristiano Ferlini, Mariagrazia Distefano, Luca Pierelli, Giuseppina
Bonanno, Antonella Riva, Ezio Bombardelli, Iwao Ojima, Salvatore Mancuso,
and Giovanni Scambia
Antimetastatic and Anti-Invasive Ability
of Phospho-ascorbyl Palmitate Through Intracellular Ascorbate Enrichment
and the Resultant Antioxidant Action
Jian-Wen Liu, Norio Nagao, Katsuhiro Kageyama, and Nobuhiko Miwa
VOLUME 11, NUMBER 9, 1999
COMMENTARY
The Role of Mismatch Repair in DNA
Damage-Induced Apoptosis
Guo-Min Li
Targeted Antiestrogens for the Prevention
of Breast Cancer
David J. Brentrem and V. Craig Jordan
LABORATORY RESEARCH
Expression of Ribosomal Protein S5
Cloned Gene During Differentiation and Apoptosis in Murine Erythroleukemia
(MEL) Cells
Ioannis S. Vizirianakis, Ioannis S. Pappas, Dimitrios Gougoumas,
and Asterios S. Tsiftsoglou
Human N-ras, TRK-T1,
and RET/PTC3 Oncogenes, Driven by a Thyroglobulin Promoter, Differently
Affect the Expression of Differentiation Markets and the Proliferation
of Thyroid Epithelial Cells
Giuseppe Portella, Donatella Vitagliano, Cristina Borselli, Rosa
Marina Melillo, Domenico Salvatore, Jay L. Rothstein, Giancarlo Vecchio,
Alfredo Fusco, and Massimo Santoro
Attenuation of the Induced Differentiation
of HL-60 Leukemia Cells by Mitochondiral Chaperone HSP70
Jian Xu, Helen Hong Xiao, and Alan C. Sartorelli
CLINICAL RESEARCH
Market Variation of Thymidylate Synthase
and Folylpolyglutamate Synthetase Gene Expression in Human Colorectal Tumors
Enrico Mini, Cristina Biondi, Maria Morganti, Cristina Napoli, Paolo
Mazzoni, Fabio Cianchi, Francesco Tonelli, Camillo Cortesini, Sergio Capaccioli,
Ferdinando Ficari, Alessandro Quattrone, Susanna Rosi, and Teresita Mazzei
VOLUME 11, NUMBER 8, 1999
COMMENTARY
Natural Killer Cells as Potential Tools
in Melanoma Metastatic Spread Control
Roberto Nasca and Ennio Carbone
LABORATORY RESEARCH
Mechanisms Involved in the Potentiation
of Melphalan by the Bioreductive Compound THNLA-1 In Vitro
Maria V. Papadopoulou, Ming Ji, Shariq H. Khan, and William D. Bloomer
Morphologic Aspect of the Placenta
in Young and Adult Pregnant Rats Bearing Walker 256 Carcinoma
Mércia Tancredo Toledo and Maria Cristina Cintra Gomes-Marcondes
Comparison of Flow Cytometry and RT-PRC
for the Detection of Ovarian Cancer Cells in Peripheral Blood
Margit Stimpfl, Bernd C. Schmid, Andreas Obermair, Dan Tong, Ingrid
Schiebel, Gerald Gitsch, Sepp Leodolter, and Robert Zeillinger
Influence of the Fluoroquinolone Ofloxacin
on the Intrinsic Expression of Multidrug Resistance Phenotype in HCT-8
Human Colon Carcinoma Cells
Sophie Marchal, Jean Louis Merlin, Pascal Colosetti, and Chantal
Finance
Combination Studies of Antifolates
With 5-Fluorouracil in Colon Cancer Cell Lines
Clasina van der Wilt, Catherina M. Kuiper, and Godefridus Peters
VOLUME 11, NUMBER 7, 1999
LABORATORY RESEARCH
Microsatellite Instability and Frameshift
Mutations in Genes Involved in Cell Cycle Progression or Apoptosis in Ovarian
Cancer
Anna Maria Cogegoni, Francesco Bertoni, Gennaro Colella, Giovanna
Caspani, Laura Grassi, Maurizio D'Incalci, and Massimo Broggini
Effects of Mitomycin C and Carboplatin
Pretreatment on Multidrug Resistance-Associated P-Glycoprotein Expression
and on Subsequent Suppression of Tumor Growth by Doxorubicin and Paclitaxel
in Human Metastatic Breast Cancer Xenografted Nude Mice
Michael A. Ihnat, Angela M. Nervi, Stephen P. Anthony, Ronald C.
Kaltreider, Amy J. Warren, Carrie A. Pesce, Stacey A. Davis, Jean P. Lariviere,
and Joshua W. Hamilton
c-erbB-2 mRNA in Breast Cancer
Specimens That Exhibit Membrane or Cytoplasmic Immunoreactivity for c-erbB-2
Sue L. Taylor, Philip S. Rudland, and Roger Baraclough
Establishment of a Quantitative Mouse
Dorsal Air Sac Model and its Application to Evaluate a New Angiogenesis
Inhibitor
Yasuhiro Funahashi, Toshiaki Wakabayashi, Taro Semba, Jiro Sonoda,
Kyosuke Kitoh, and Kentaro Yoshimatsu
Sodium Butyrate Modulates p53 and Bcl-2
Expression in Human Retinoblastoma Cell Lines
Michele C. Madigan, Geeta Chaudhri, Philip L. Penfold, and Robert
M. Conway
VOLUME 11, NUMBER 6, 1999
LABORATORY RESEARCH
Inhibition of the Action of the Topoisomerase
II Poison Amsacrine by Simple Aniline Derivatives: Evidence for Drug-Protein
Interactions
Graeme J. Finlay, Graham J. Atwell, and Bruce C. Baguley
The Protective Effect of Estrogen Against
Chemically Induced Murine Colon Carcinogenesis Is Associated With Decreased
CpG Island Methylation and Increased mRNA and Protein Expression of the
Colonic Vitamin D Receptor
Patricia Smirnoff, Yair Liel, Julia Gnainsky, Shraga Shany, and
Betty Schwartz
Influence of Static Magnetic Field
on the Antiproliferative Effects of Vitamin D on Human Breast Cancer Cells
Stefania Pacini, Stefano Aterini, Paolo Pacini, Carla Ruggiero,
Massimo Gulisano, and Marco Ruggiero
Growth Inhibition of a Human Ovarian
Tumor by a Novel Paclitaxel Derivative in SCID Mice
Imran Ahmad, Gregg R. Masters, James J. Schupsky, Josephine Nguyen,
Shaukat Ali, Andrew S. Janoff, and Eric Mayhew
Identification of Seven Genes Regulated
by Wild-Type p53 in a Colon Cancer Cell Line Carrying a Well-Controlled
Wild-Type p53 Expression System
Shu Okamura, Ching C. Ng, Kumiko Koyama, Yoshiki Takei, Hirofumi
Arakawa, Morito Monden, and Yusuke Nakamura
Neuroprotective Interactions in Rats
Between Paclitaxel and Cisplatin
Mark J. McKeage, Gabi G. Haddad, Li Ding, Peter Galettis, Daniela
Screnci, Li Zhuang, and Bruce C. Baugley
VOLUME 11, NUMBER 5, 1999
LABORATORY RESEARCH
Characteristics of Human T-Lymphotropic
Virus Type-1 (HTLV-1)-Infected Cell Line MT-2, Which Is Not Killed by a
Natural Killer Cell Line NK-92 But Is Killed by Lymphokine-Activated Killer
Cells
Fumio Komatsu and Sayaka Yoshida
Therapeutic Efficacy of a New Topoisomerase
I and II Inhibitor TAS-103, Against Both P-Glycoprotein-Expressing and\T\\Nonexpressing
Drug-Resistant Human Small-Cell Lung Cancer
Prahlad Parajuli, Seiji Yano, Yasuhiko Nishioka, Hiroshi Nokihara,
Masaki Hanibuchi, Naoki Nishimura, Teruhior Utsugi, and Saburo Sone
Anticancer Potential of Cleistanthin
A Isolated From the Tropical Plant Cleistanthus collinus
Chhalliyil P. Pradheepkumar and Govindaswamy Shanmugam
Carbohydrate Epitopes and Mucins Expressed
by 17 Human Ovarian Carcinoma Cell Lines
Yutaka Tamada, Shin-ichiro Iida, Daisuke Aoki, Shiro Nozawa, and
Tatsuro Irimura
Ribavirin and Quercetin Synergistically
Downregulate Signal Transduction and Are Cytotoxic in Human Ovarian Carcinoma
Cells
W. Li, F. Shen, and G. Weber
VOLUME 11, NUMBER 4, 1999
COMMENTARY
The Metastatic Process: Basic Research
and Clinical Implications
Ann F. Chambers
Cellular Basis of Breast Cancer Susceptibility
J. Russo and I. H. Russo
LABORATORY RESEARCH
The Effects of Vasodilating Drugs on
pH in Tumors
Eisuke Adachi and Ian F. Tannock
Inhibition of Interleukin-8 Reduces
Human Malignant Pleural Mesothelioma Propagation in Nude Mouse Model
Gabriella Galffy, Kamal A. Mohammed, Najmunnisa Nasreen, Melisa
J. Ward, Veena B. Antony
9-(2-Phosphonylmethoxyethyl)-N6-Cyclopropyl-2,6-Diaminopurine:
A Novel Prodrug of 9-(2-Phosphonylmethoxyethyl)Guanine With Improved Antitumor
Efficacy and Selectivity in Choriocarcinoma-Bearing Rats
Lieve Naesens, Sigrid Hatse, Constant Segers, Erik Verbeken, Erik
De Clercq, Mark Waer, and Jan Balzarini
CLINICAL RESEARCH
Intratumoral Angiogenesis: A New Prognostic
Indicator for Stage I Endometrial Adenocarcinomas?
Alexandra Giatromanolaki, Efthimios Sivridis, Michael I. Koukourakis,
Vassilios Georgoulias, Kevin C. Gatter, and Adrian L. Harris
VOLUME 11, NUMBER 3, 1999
COMMENTARY
The Development of Awareness of the
Carcinogenic Hazard of Inhaled Iron
Eugene D. Weinberg
Short-Term Cultures of Clinical Tumor
Material: Potential Contributions to Oncology Research
Bruce C. Baguley, Elaine S. Marshall, and Graeme J. Finlay
LABORATORY RESEARCH
Induction of Apoptosis in T98G Glioblastoma
Cells by Transfection of GML, a p53 Target Gene
Kazuki Ueda, Yasuo Miyoshi, Takashi Tokino, Masahiro Watatani, and
Yusuke Nakamura
Antitumor Effect of Vaccinia Virus
in Glioma Model
Tatyana M. Timiryasova, Jun Li, Bind Chen, Daneil Chong, William
H. Langridge, Daila S. Gridley, and Istvan Fodor
Biological Evaluation on Different
Human Cancer Cell Lines of Novel Colchicine Analogs
Rosa De Vincenzo, Cristiano Ferlini, Mariagrazia Distefano, Christiana
Gaggini, Antonella Riva, Ezio Bombardelli, Paolo Morazzoni, Bruno Danieli,
Giovanni Capelli, Salvatore Mancuso, and Giovanni Scambia
In Vivo Studies of Adenovirus-Mediated
p53 Gene Therapy for cis-Platinum-Resistant Human Ovarian Tumor
Xenografts
Kaimei Song, Kenneth H. Cowan, and Birandra K. Sinha
VOLUME 11, NUMBER 2, 1999
COMMENTARY
BRCA1 and BRCA2 Gene Mutation Analysis:
Visit to the Breast Cancer Information Core (BIC)
Dejun Shen, Jaydutt V. Vadgama, and Breast Cancer Information Core
LABORATORY RESEARCH
Differences in Apoptosis Induced by
Anticancer Drugs in Sublines (SKG-3a, SKG-3b) From a Human Uterine Cervical
Epidermoid Carcinoma
Motoo Takahashi, Shiro Kataoka, Eiichi Kobayashi, Yasuhiro Udagawa,
Daisuke Aoki, Shinji Oie, Akiko Kozu, and Shiro Nozawa
Mechanism of Antimitogenic Action of
Vitamin D in Human Colon Carcinoma Cells: Relevance for Suppression of
Epidermal Growth Factor-Stimulated Cell Growth
Wei-Min Tong, Harald Hofer, Adolf Ellinger, Meinrad Peterlik, and
Heide S. Cross
Downregulation of TNF Receptor-Associated
Protein-2/p97 in Renal Cell Carcinoma
Marike J. J. G. Stassar, Claudia Pitzer, and Margot Zöller
Dimerization of Mitochondrial Bax Is
Associated With Increased Drug Response in Bax-Transfected A253 Cells
Bin Guo, Ming-biao Yin, Károly Tóth, Shousong Cao,
Rami G. Azrak, and Youcef M. Rustum
CLINICAL RESEARCH
Infrequent Genetic Alterations of p53,
p16 Genes and Polymorphism in fhit Gene in Indian Myelodysplastic
Syndrome
Karuppiah Kannan, Reeja Tharu, P. M. Gopinath, T. P. R. Bharadwaj,
Arasampattu K. Munirajan, Nobuo Tsuchida, and Govindaswamy Shanmugam
Reproduction of Figures
Marjo Seppänen, Tiina Henttinen, Lin Lin, Juha Punnonen, Seija
Grénman, Reijo Punnonen, and Kimmo K. Vihko
VOLUME 11, NUMBER 1, 1999
COMMENTARY
In Situ Gene Therapy for Prostate Cancer
Timothy C. Thompson
LABORATORY RESEARCH
Sterically Stabilized Anti-GM3,
Anti-Lex Immunoliposomes: Targeting to B16BL6, HRT-18 Cancer
Cells
Sang Min Nam, Hong Sung Kim, Woong Shick Ahn, and Yong Serk Park
Osteoblasts Modulate Secretion of Urokinase-Type
Plasminogen Activator (uPA) and Matrix Metalloproteinase-9 (MMP-9) in Human
Prostate Cancer Cells Promoting Migration and Matrigel Invasion
Claudio Festuccia, Daniela Giunciuglio, Fulvio Guerra, Ida
Villanova, Adriano Angelucci, Paola Manduca, Anna Teti, Adrianna Albini,
and Mauro Bologna
Verotoxin Induces Apoptosis and the
Complete, Rapid, Long-Term Elimination of Human Astrocytoma Xenografts
in Nude Mice
Sara Arab, James Rutka, and Clifford Lingwood
Characterization of Selective Induction
and Alteration of Xenobiotic Biotransforming Enzymes by Vanadium During
Diethylnitrosamine-Induced Chemical Rat Liver Carcinogenesis
Anuspam Bishayee, Shyamal Roy, and Malay Chatterjee
CLINICAL RESEARCH
Melanoma-Inhibitory Activity Protein
Concentrations in the Blood of Melanoma Patients Treated With Immunotherapy
D. Dréau, A. K. Bosserhoff, R. L. White, R. Buettner, and
W. D. Holder