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ognizant Communication Corporation |
ONCOLOGY RESEARCH
AN INTERNATIONAL JOURNAL
INCORPORATING ANTI-CANCER DRUG
DESIGN
TABLES OF CONTENTS
VOLUME 13
Understanding the Selectivity
of Fumagillin for the Methionine Aminopeptidase Type II
Christian D. P. Klein and G. Folkers
In Vitro Antitumor SAR
of threo/cis/threo/cis/erythro bis-THF Acetogenins: Correlations
With Their Inhibition of Mitochondrial Complex I
Inmaculada Royo, Nuria DePedro, Ernesto Estornell, Diego Cortes,
Fernando Peláez, and José R. Tormo
SAR: Flavonoids and COX-2
Inhibition
Herbert S. Rosenkranz and Bhavani P. Thampatty
Synthesis and Antiproliferative
Activity of Basic Ethers of 1,2-Dihydropyrrolo[1,2-a]indole, 6H-Isoindolo[2,1-a]indole,
and 6H-Benz[5,6]isoindolo[2,1-a]indole
Jean Guillaumel, Stéphane Léonce, Alain Pierré,
Pierre Renard, Bruno Pfeiffer, Laure Peruchon, Paola B. Arimondo, and Claude
Monneret
Molecular and Functional
Characterization of the Extracellular Calcium-Sensing Receptor in Human
Colon Cancer Cells
Enikö Kállay, Elisabeth Bonner, Friedrich Wrba, Rajesh
V. Thakker, Meinrad Peterlik, and Heide S. Cross
Synergistic Interaction
Between Cyclophosphamide or Paclitaxel and the Bioreductive Compound NLCPQ-1,
In Vivo
M. V. Papadopoulou, M. Ji, and W. D. Bloomer
Volume 13 Subject and Author Index
VOLUME 13, NUMBER 11
Laboratory Research
Novel Sigma Binding Site
Ligands as Inhibitors of Cell Proliferation in Breast Cancer
Federica Barbieri, Anna Sparatore, Angela Alama, Federica Novelli,
Cristina Bruzzo, and Fabio Sparatore
Flavonoids as Inhibitors
of MRP1-Like Efflux Activity in Human Erythrocytes. A Structure-Activity
Relationship Study
Malgorzata Bobrowska-Hägerstrand, Anna Wróbel, Lucyna
Mrówczynska, Thomas Söderström, Yoshiaki Shirataki, Noboru
Motohashi, Joseph Molnár, Krystyna Michalak, and Henry Hägerstrand
Three-Dimensional Pharmacophore
Mapping of Certain Anticancer a-Methylene-g-Butyrolactones
Kuan-Han Lee and Bor-Ruey Huang
Detection of Labile Anthracycline-DNA
Adducts By Real-Time PCR
Damian M. S. Spencer, Suzanne M. Cutts, Ken-ichi Kimura, Peter J.
Gray, and Don R. Phillips
Mode of Cell Death Induced
in Chinese Hamster Cells by Sequence-Selective DNA Minor Groove Binding
Nitrogen Mustards: Comparison With Untargeted Mustards and With Hoechst
33342
Glenn Whiteside, Lynnette R. Ferguson, William A. Denny, and Iona
E. Weir
Synthesis and Antimelanoma
Activity of Tertiary Amide Analogues of N-Acetyl-4-S-cysteaminylphenol
Vikki C. Pearson, Jillian Ferguson, Paul M. Rogers, Lloyd R. Kelland,
and David J. Robins
VOLUME 13, NUMBERS 6-10
SPECIAL ISSUE FROM THE 2001 MILLENNIUM INTERNATIONAL CONFERENCE OF MOLECULAR AND TUMOR BIOLOGY
Introduction
Asterios S. Tsiftsoglou and Bing Lim, Guest Editors
Commentary: Nuclear Reprogramming and the Redirection of Cell Fate
in Xenopus
John B. Gurdon
Somatic Cell Nuclear Transfer
Ian Wilmut and Lesley Paterson
Cloned Mice and Embryonic
Stem Cell Lines Generated From Adult Somatic Cells by Nuclear Transfer
Teruhiko Wakayama
Developmental Origins of
Hematopoietic Stem Cells
C. Robin, K. Ottersbach, M. de Bruijn, X. Ma, K. van der Horn, and
E. Dzierzak
RhoGTPases and Their Role
in Cancer
Xiaoyu Li and Bing Lim
Analyzing Tumor Suppressor
Activities in the Murine Small Intestine
Alan R. Clarke and Owen J. Sansom
The Developmental Program
of Murine Erythroleukemia Cells
Asterios S. Tsiftsoglou, Ioannis S. Pappas, and Ioannis S. Vizirianakis
Small Molecule Regulation
of Phosphatase-Dependent Cell Signaling Pathways
John S. Lazo and Peter Wipf
Isolation and Characterization
of Normal Adult Human Epithelial Pluripotent Stem Cells
James E. Trosko and Chia-Cheng Chang
Functional Cloning of IGFBP-3
From Human Microvascular Endothelial Cells Reveals its Novel Role in Promoting
Proliferation of Primitive CD34+CD38- Hematopoietic
Cells In Vitro
Li-Qin Liu, Margaret Sposato, Hai-Yan Liu, Tracy Vaudrain, Meng-Jiao
Shi, Kristin Rider, Zack Stevens, Jan Visser, Hong-Kui Deng, and Morey
Kraus
Insights Into the Role of
DNA Methylation in Murine Embryonic Stem Cells Using a Modified Tetracycline-Inducible
Gene Expression System
Timothy Chevassut and Bing Lim
Emerging Interest in the
Kallikrein Gene Family for Understanding and Diagnosing Cancer
Georgia Sotiropoulou, Vassilios Rogakos, Theodoros Tsetsenis, Georgios
Pampalakis, Nikolaos Zafiropoulos, George Simillides, Athanassios Yiotakis,
and Eleftherios P. Diamandis
Identification of Keratinocyte
Proteins That Mark Subsets of Cells in the Epidermal Stratum Basale: Comparisons
With the Intestinal Epithelium
Sally Dabelsteen, Jesper T. Troelsen, and Jorgen Olsen
Cisplatin Resistance in
an Ovarian Carcinoma Is Associated With a Defect in Programmed Cell Death
Control Through XIAP Regulation
Abdellah Mansouri, Qingxiu Zhang, Lon D. Ridgway, Ling Tian, and
Francois-Xavier Claret
A New Method for Determining
the Status of p53 in Tumor Cell Lines of Different Origin
Andrei L. Gartel, Claudine Feliciano, and Angela L. Tyner
Brk, Srm, Frk, and Src42A
Form a Distinct Family of Intracellular Src-Like Tyrosine Kinases
Michael S. Serfas and Angela L. Tyner
Structural Genomics of Lipid
Signaling Domains
Yosuke Tsujishita
Differentially Expressed
Downstream Genes in Cells With Normal or Mutated p53
Hao Xu and M. Raafat El-Gewely
Oncoselective Parvoviral
Vector-Mediated Gene Therapy of Cancer
Marc Zeicher, Pierre Spegelaere, Marie Horth, David Gancberg, Abdelatif
Karim, and Francis Dupont
Control of Hematopoietic
Stem/Progenitor Cell Fate by Transforming Growth Factor-b
Nicolas Olivier Fortunel, Jacques Alexandre Hatzfeld, Marie-Noëlle
Monier, and Antoinette Hatzfeld
VOLUME 13, NUMBER 5
Laboratory Research
Differential Ability of Cytostatics
From Anthraquinone Group to Generate Free Radicals in Three Enzymatic Systems:
NADH Dehydrogenase, NADPH Cytochrome P450 Reductase, and Xanthine Oxidase
Jolanta Pawlowska, Jolanta Tarasiuk, C. Roland Wolf, Mark J. I.
Paine, and Edward Borowski
Involvement of ERK1/2 in
Invasiveness and Metastatic Development of Rat Prostatic Adenocarcinoma
Tuangporn Suthiphongchai, Piradee Promyart, Sariya Virochrut, Rutaiwan
Tohtong, and Prapon Wilairat
Significant Experimental
Decrease of the Hepatocellular Carcinoma Incidence in C3H/Sy
Mice After Long-Term Administration of EB1089, a Vitamin D Analogue
Despina Sahpazidou, Pelagia Stravoravdi, Theano Toliou, George Geromichalos,
George Zafiriou, Konstantinos Natsis, and Panagiotis Gigis
Cytotoxicity and Cell Cycle
Effects of Novel Indolo[2,3-b]quinoline Derivatives
Rita Humeniuk, Lukasz Kaczmarek, Wanda Peczynska-Czoch, and Ewa
Marcinkowska
Resistance of Decoy PNA-DNA
Chimeras to Enzymatic Degradation in Cellular Extracts and Serum
Monica Borgatti, Alessandra Romanelli, Michele Saviano, Carlo Pedone,
Ilaria Lampronti, Laura Breda, Claudio Nastruzzi, Nicoletta Bianchi, Carlo
Mischiati, and Roberto Gambari
Clinical Research
Phosphorylation, But Not Overexpression, of Epidermal Growth Factor
Receptor Is Associated With Poor Prognosis of Non-Small Cell Lung Cancer
Patients
Takanori Kanematsu, Seiji Yano, Hisanori Uehara, Yoshimi Bando,
and Saburo Sone
VOLUME 13, NUMBER 4
Laboratory Research
Synthesis of 6-Dialkylaminoalkylamino
Pyrano[2,3-c]Acridones and Benzo[b]Pyrano[3,2-h]Acridones:
Soluble Acronycine Analogues With Increased Cytotoxic Activity
Nadine Costes, Abdelhakim Elomri, Hanh Dufat, Sylvie Michel, Elisabeth
Seguin, Michel Koch, François Tillequin, Bruno Pfeiffer, Pierre
Renard, Stéphane Léonce, and Alain Pierré
Synthesis and Biological
Evaluation of Novel bis-Aziridinylnaphthoquinone Derivatives
Sheng-Tung Huang, Hsien-Shou Kuo, Chun-Mao Lin, Hsin-Da Tsai, Yi-Chen
Peng, Chien-Tsu Chen, and Yuh-Ling Lin
Evaluation of O6-Methylguanine
DNA Methyltransferase Activity in Patients With Gastric Cancer
Yïldïz Dinçer, Tülay Akçay, Osman B.
Tortum, Zeynep Alademir, Sinan Önen, and Gülen Dogusoy
Modeling Plasma and Saliva
Topotecan Concentration Time Course Using a Population Approach
Maud Boucaud, Frédéric Pinguet, Stéphane Culine,
Sylvain Poujol, Cécile Astre, Roberto Gomeni, and Françoise
Bressolle
Synthesis and Antitumor Cytotoxicity
Evaluation of Novel Pyrrolo[2,1-c][1,4]benzodiazepine Imidazole
Containing Polyamide Conjugates
Rohtash Kumar and J. William Lown
Lymphokine-Activated Killer
Cells Can Kill Target Cells Not Only by Early Killing But Also by Late
Killing, and the Late Killing Level Against Autotumor Cell Line
Fumio Komatsu and Kiyomi Ishiguro
Erratum
VOLUME 13, NUMBER 3
Review
Development of Polyamine
Analogs as Cancer Therapeutic Agents
Thresia Thomas, Srivani Balabhadrapathruni, Michael A. Gallo, and
T. J. Thomas
Laboratory Research
Constitutive Production of
Parathyroid Hormone-Related Protein (PTHrP) by Fibroblasts Derived From
Normal and Pathological Human Breast Tissue
Magali Cros, Christophe Cataisson, Yong Mee Cho, Yolande Berthois,
Oana Bernard-Poenaru, Maryannick Denne, Anne-Marie Graulet, Marie-Christine
De Vernejoul, John Foley, and Zhor Bouizar
Embryonal Mass and Hormone-Associated
Effects of Pregnancy Inducing a Differential Growth of Four Murine Tumors
Oscar D. Bustuoabad, Pedro D. di Gianni, Marcela Franco, Edith C.
Kordon, Silvia I. Vanzulli, Roberto P. Meiss, Lorena C. Grion, Graciela
S. Díaz, Sergio H. Nosetto, Pablo Hockl, M. Gabriela Lombardi, Christiane
Dosne Pasqualini, and Raúl A. Ruggiero
Analysis of Differentially
Expressed Genes in Hepatocellular Carcinoma With Hepatitis C Virus by Suppression
Subtractive Hybridization
Masayo Kotaka, George G. Chen, Paul B. S. Lai, Wan Y. Lau, Paul
K. S. Chan, Thomas W. T. Leung, and Arthur K. C. Li
A Sensitive Bioassay for
Measuring Blood Levels of 12-O-Tetradecanoylphorbol-13-acetate (TPA)
in Patients: Preliminary Pharmacokinetic Studies
Xiao Xing Cui, Richard L. Chang, Xi Zheng, Donald Woodward, Roger
Strair, and Allan H. Conney
Antitumor Polycyclic Acridines.
Part 12. Physical and Biological Properties of 8,13-Diethyl-6-methylquino[4,3,2-kl]acridinium
Iodide: A Lead Compound in Anticancer Drug Design
Sotiris Missailidis, Johnson Stanslas, Chetna Modi, Michael J. Ellis,
R. Adrian Robins, Charles A. Laughton, and Malcolm F. G. Stevens
VOLUME 13, NUMBER 2
Laboratory Research
Stimulatory Effect of Topical
Application of Caffeine on UVB-Induced Apoptosis in Mouse Skin
Yao-Ping Lu, You-Rong Lou, Xiang-Hong Li, Jian-Guo Xie, Yong Lin,
Weichung Joe Shih, and Allan H. Conney
Low Molecular Weight Hyaluronan
Induces Malignant Mesothelioma Cell (MMC) Proliferation and Haptotaxis:
Role of CD44 Receptor in MMC Proliferation and Haptotaxis
Najmunnisa Nasreen, Kamal A. Mohammed, Joyce Hardwick, Robert D.
Van Horn, Kerry Sanders, Hasmeena Kathuria, Farzad Loghmani, and Veena
B. Antony
Adherence of Ovarian Cancer
Cells Induces Pleural Mesothelial Cell (PMC) Permeability
P. S. Sriram, Kamal A. Mohammed, Najmunnisa Nasreen, Joyce Hardwick,
Robert Van Horn, Kerry Sanders, and Veena B. Antony
Glucocorticoids Induce Neuroendocrine
Cell Differentiation and Increase Expression of N-myc in N-type
Human Neuroblastoma Cells
Robert A. Ross, Anne M. Hein, John A. Braca, III, Barbara A. Spengler,
June L. Biedler, and Jonathan G. Scammell
Uptake of the Antivascular
Agent 5,6-Dimethylxanthenone-4-Acetic Acid (DMXAA) and Activation of NF-kB
in Human Tumor Cell Lines
See-Tarn Woon, Bruce C. Baguley, Brian D. Palmer, John D. Fraser,
and Lai-Ming Ching
Immunoglobulin Superfamily
Expression in Primary Retinoblastoma and Retinoblastoma Cell Lines
Michele C. Madigan, Philip L. Penfold, Nicholas J. C. King, Francis
A. Billson, and Robert M. Conway
The Possible Correlation
Between Activation of NF-kB/IkB
Pathway and the Susceptibility of Tumor Cells to Paclitaxel-Induced Apoptosis
Yi Huang, Yong Fang, Jennifer M. Dziadyk, James S. Norris, and Weimin
Fan
VOLUME 13, NUMBER 1
Editorial
Oncology Research Incorporating Anti-Cancer Drug Design
Stephen Neidle and Alan C. Santorelli
Commentary
Pigmentation in Melanomas:
Changes Manifesting Underlying Oncogenic and Metabolic Activities
Ruth Halaban
Laboratory Research
Dose and Timing of Total-Body
Irradiation Mediate Tumor Progression and Immunomodulation
Glen M. Miller, Eric H. Kajioka, Melba L. Andres, and Daila S. Gridleya
Exposure to Global System
for Mobile Communication (GSM) Cellular Phone Radiofrequency Alters Gene
Expression, Proliferation, and Morphology of Human Skin Fibroblasts
Stefania Pacini, Marco Ruggiero, Iacopo Sardi, Stefano Aterini,
Franca Gulisano, and Massimo Gulisano
Verapamil Reverts Resistance
to Drug-Induced Apoptosis in Ki-ras-Transformed Cells by Altering
the Cell Membrane and the Mitochondrial Transmembrane Potentials
Daniela Spalletti-Cernia, Igea D'Agnano, Rosanna Sorrentino, Gabriella
Zupi, Giancarlo Vecchio, Giuseppe Portella, and Paolo Laccetti
Inhibition of Mouse Skin
Tumor Promotion by Anti-Inflammatory Diarylheptanoids Derived From Alpinia
oxyphylla Miquel (Zingiberaceae)
Kyung-Soo Chun, Kwang-Kyun Park, Jeewoo Lee, Myungshim Kang, and
Young-Joon Surh
Synergistic Enhancement of
the Antitumor Effect of Taxol by the Bioreductive Compound NLCQ-1, In Vivo:
Comparison With Tirapazamine
Maria V. Papadopoulou, Ming Ji, and William D. Bloomer
Clinical Research
Epithelioid Granulomas as
Main Clinical Manifestation at the Outset of Non-Hodgkin's Lymphoma: Report
of Two Cases
Roberto Lerza, Emanuela Schenone, Bianca Paola Barsotti, Marco Botta,
Eleonora Arboscello, Mauro Truini, Giuseppe Bogliolo, and Ivo Pannacciulli