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ognizant Communication Corporation |
ONCOLOGY RESEARCH
AN INTERNATIONAL JOURNAL
INCORPORATING ANTI-CANCER DRUG
DESIGN
TABLES OF CONTENTS
VOLUME 14
VOLUME 14, NUMBERS 11/12
Review
Copper Chelation as an
Antiangiogenic Therapy
S. A. Lowndes and A. L. Harris
Laboratory Research
Design and Construction
of a Phosphorylatable Chimeric Monoclonal Antibody With a Highly Stable
Phosphate
Wei Wu, John E. Kerrigan, Prem Yadav, Barbara Schwartz, Lara Izotova,
Thomas B. Lavoie, and Sidney Pestka
Radiation-Induced Sensitizing
Effect of Folic Acid (Vitamin B11) and its Synergistic Action
to Mitomycin C: In Vitro Experiments and Radiolysis
Alexandra Delipetar-Grudl and Nikola Getoff
Resistance of Ovarian Carcinoma
Cells to Docetaxel Is XIAP Dependent and Reversible by Phenoxodiol
Eva Sapi, Ayesha B. Alvero, Wei Chen, David O'Malley, Xiao-Ying
Hao, Bambang Dwipoyono, Manish Garg, Marijke Kamsteeg, Thomas Rutherford,
and Gil Mor
The Unique Biological Features
of the Marine Product YondelisTM (ET-743, Trabectedin) Are Shared
by its Analog ET-637, Which Lacks the C Ring
E. Erba, E. Cavallaro, G. Damia, R. Mantovani, A. Di Silvio, A.
M. Di Francesco, R. Riccardi, C. Cuevas, G. T. Faircloth, and M. D'Incalci
secErbB4-26/549 Antagonizes
Ligand-Induced ErbB4 Tyrosine Phosphorylation
Jennifer L. Gilmore and David J. Riese, II
Clinical Research
Serum Levels of Soluble
E-Selectin Are Associated With the Clinical Course of Metastatic Disease
in Patients With Liver Metastases From Breast Cancer
Michael H. R. Eichbaum, Thomas M. de Rossi, Sepp Kaul, and Gunther
Bastert
Concentrations of VEGF
and VEGFR1 in Paired Tumor Arteries and Veins in Patients With Rectal Cancer
Mads N. Svendsen, Jakob Lykke, Kim Werther, Ib J. Christensen, and
Hans J. Nielsen
Volume 14 Subject and Author Index
VOLUME 14, NUMBER 10
Laboratory Research
The Ability of New Sugar-Modified
Derivatives of Antitumor Anthracycline, Daunorubicin, to Stimulate NAD(P)H
Oxidation in Different Cellular Oxidoreductase Systems: NADH Dehydrogenase,
NADPH Cytochrome P450 Reductase, and Xanthine Oxidase
Jolanta Pawlowska, Waldemar Priebe, Mark J. I. Paine, C. Roland
Wolf, Edward Borowski, and Jolanta Tarasiuk
PAR1-Type Thrombin
Receptor Stimulates Migration and Matrix Adhesion of Human Colon Carcinoma
Cells by a PKCe-Dependent Mechanism
Ilonka Heider, Beate Schulze, Elke Oswald, Peter Henklein, Johannes
Scheele, and Roland Kaufmann
Nicotinamide Relaxes Vascular
Smooth Muscle by Inhibiting Myosin Light Chain Kinase-Dependent Signaling
Pathways: Implications for Anticancer Efficacy
Mark W. Ruddock and David G. Hirst
The Differential Proteome
Profile of Stomach Cancer: Identification of the Biomarker Candidates
Joung S. Jang, Hee Y. Cho, Young J. Lee, Woo S. Ha, and Hwal W.
Kim
Proteolysis of Human Plasma
Reveals the Presence of Complexes Formed by Endogenous Heparin and Peptides
That Stimulate Angiogenesis
Stefania Pacini, Marco Ruggiero, Fabiola Cecchi, Benedetta Peruzzi,
and Simonetta Vannucchi
In Vivo Molecular Pharmacology
and Antitumor Activity of the Targeted Akt Inhibitor PX-316
Emmanuelle J. Meuillet, Nathan Ihle, Amanda F. Baker, Jaime M. Gard,
Chelsea Stamper, Ryan Williams, Amy Coon, Daruka Mahadevan, Benjamin L.
George, Lynn Kirkpatrick, and Garth Powis
VOLUME 14, NUMBER 9
Laboratory Research
4-[3,5-bis(trimethylsilyl)benzamido]
Benzoic Acid Inhibits Angiogenesis in Colon Cancer Through Reduced Expression
of Vascular Endothelial Growth Factor
Noritaka Minagawa, Yoshifumi Nakayama, Yuzuru Inoue, Koji Onitsuka,
Takefumi Katsuki, Yosuke Tsurudome, Kazunori Shibao, Keiji Hirata, Tatsuhiko
Sako, Naoki Nagata, Shinji Ohie, Kimitoshi Kohno, and Hideaki Itoh
Resveratrol and Propolis
as Necrosis or Apoptosis Inducers in Human Prostate Carcinoma Cells
Christian Scifo, Venera Cardile, Alessandra Russo, Rosanna Consoli,
Carlo Vancheri, Francesco Capasso, Angelo Vanella, and Marcella Renis
Modulation of Wnt-Specific
Colon Cancer Cell Kill by Butyrate and Lithium
Michael Bordonaro, Darina L. Lazarova, Rocco Carbone, and Alan C.
Sartorelli
Cell-Free DNA and RNA in
Plasma as a New Molecular Marker for Prostate Cancer
Eirini Papadopoulou, Elias Davilas, Vasilios Sotiriou, Alexander
Koliopanos, Filipos Aggelakis, Konstantinos Dardoufas, Niki J. Agnanti,
Irini Karydas, and Georgios Nasioulas
Radiosensitization of Colon
Cancer Cell Lines by Docetaxel: Mechanisms of Action
Amanda L. Dunne, Carmel Mothersill, Tracy Robson, George D. Wilson,
and David G. Hirst
PEG Prodrugs of 6-Mercaptopurine
for Parenteral Administration Using Benzyl Elimination of Thiols
Yun H. Choe, Richard B. Greenwald, Charles D. Conover, Hong Zhao,
Clifford B. Longley, Shuiyun Guan, Qiuxia Zhao, and Jing Xia
VOLUME 14, NUMBERS 7/8
Brief Communication
Diagnostic, Endocrinological,
Behavioral, and DNA Ploidy Differences Between Squamous Cell and Adenomatous
Carcinoma of the Cervix Uteri
Annika Kristina Lindström, Dan Hellberg, Torbjörn Bäckström,
and Ulf Stendahl
Effect of Association of
Temozolomide With Other Chemotherapic Agents on Cell Growth Inhibition
in Glioma Cell Lines
Marco Balzarotti, Emilio Ciusani, Chiara Calatozzolo, Danilo Croci,
Amerigo Boiardi, and Andrea Salmaggi
Laboratory Research
Age-Related Differences in
Vincristine Toxicity and Biodistribution in Wild-Type and Transporter-Deficient
Mice
Toshinari Muramatsu, Dennis R. Johnson, Rick A. Finch, Linda K.
Johnson, Janine J. Leffert, Z. Ping Lin, Giuseppe Pizzorno, and Alan C.
Sartorelli
The Cellular Response to
PPARg Ligands Is Related to the Phenotype of
Neuroblastoma Cell Lines
Tiziana Servidei, Roberta Morosetti, Cristiano Ferlini, Gabriella
Cusano, Giovanni Scambia, Renato Mastrangelo, and H. Phillip Koeffler
Screening Novel, Potent Multidrug-Resistant
Modulators From Imidazole Derivatives
Li-ming Chen, Xing-Ping Wu, Ji-wu Ruan, Yong-ju Liang, Yan Ding,
Zhi Shi, Xiu-wen Wang, Lian-Quan Gu, and Li-wu Fu
Apoptosis of Human T-Cell
Acute Lymphoblastic Leukemia Cells by Diphenhydramine, an H1 Histamine
Receptor Antagonist
Shawkat-Muhialdin Jangi, Aintzane Asumendi, Jon Arlucea, Naiara
Nieto, Gorka Perez-Yarza, María C. Morales, María de la Fuente-Pinedo,
and María D. Boyano
Status of Methylthioadenosine
Phosphorylase and its Impact on Cellular Response to L-Alanosine and Methylmercaptopurine
Riboside in Human Soft Tissue Sarcoma Cells
WeiWei Li, Dan Su, Hiroo Mizobuchi, Daniel S. Martin, Bin Gu, Richard
Gorlick, Peter Cole, and Joseph R. Bertino
Differential Effects of Doxorubicin
and Docetaxel on Nitric Oxide Production and Inducible Nitric Oxide Synthase
Expression in MCF-7 Human Breast Cancer Cells
Gulperi Oktem, Bulent Karabulut, Nur Selvi, Canfeza Sezgin, Ulus
Ali Sanli, Ruchan Uslu, Mine Ertem Yurtseven, and Serdar Bedii Omay
Inhibitory Effect of Topical
Applications of Nondenatured Soymilk on the Formation and Growth of UVB-Induced
Skin Tumors
Mou-Tuan Huang, Jian-Guo Xie, Connie B. Lin, Menas Kizoulis, Miri
Seiberg, Stanley Shapiro, and Allan H. Conney
Evidence That General Genomic
Hypomethylation and Focal Hypermethylation Are Two Independent MolecularEevents
of Non-Hodgkin's Lymphoma
Janelle T. Pini, Maria Franchina, Jeremy M. E. Taylor, and Peter
H. Kay
VOLUME 14, NUMBER 6
Review
Structural Insights Into
AGC Kinase Inhibition
Christine Breitenlechner, Michael Gaßel, Richard Engh, and
Dirk Bossemeyer
Laboratory Research
Formation of Mitoxantrone
Adducts in Human Tumor Cells: Potentiation by AN-9 and DNA Methylation
Belinda S. Parker, Ada Rephaeli, Abraham Nudelman, Don R. Phillips,
and Suzanne M. Cutts
Minimal Residual Disease
in Neuroblastoma: To GAGE or not to GAGE
S. Oltra, F. Martínez, C. Orellana, E. Grau, J. M. Fernández,
A. Cañete, and V. Castel
Estimation of Radiation-Induced
Interphase Cell Death in Cultures of Human Tumor Material and in Cell Lines
Elaine S. Marshall, Bruce C. Baguley, John H. L. Matthews, Chakiath
C. Jose, Christopher E. Furneaux, James H. F. Shaw, James A. Kirker, Randall
P. Morton, Julian B. White, Michael L. Rice, Richard J. Isaacs, Richard
Coutts, and John R. Whittaker
A Scalable High-Content Cytotoxicity
Assay Insensitive to Changes in Mitochondrial Metabolic Activity
Andreas Vogt, Erica N. Kalb, and John S. Lazo
Clinical Research
Metabolic Polymoryphisms,
Smoking, and Oral Cancer in Puerto Rico
Heng Xie, Lifang Hou, Peter G. Shields, Deborah M. Winn, Gloria
Gridley, Eleuterio Bravo-Otero, Scott R. Diehl, Elise D. Bowman, Linda
M. Brown, and Richard B. Hayes
VOLUME 14, NUMBERS 4/5
REVIEW
Emerging Roles of Targeted
Small Molecule Protein-Tyrosine Kinase Inhibitors in Cancer Therapy
John K. Smith, Naila M. Mamoon, and Roy J. Duhé
Inhibition of Angiogenesis
by Salmosin Expressed In Vitro
Soo In Kim, Keun Sik Kim, Hong Sung Kim, Myoung Min Choi, Doo Sik
Kim, Kwang Hoe Chung, and Yong Serk Park
Hydroxyurea-Induced Apoptosis
in an EBV-Immortalized Lymphoblastoid Cell Line
Pauline Huyghe, Laurent Dassonneville, Pierre Fenaux, and Christian
Bailly
Synthesis and In Vitro Cytotoxicity
Studies of Novel L-Tryptophan-Polyamide Conjugates and L-Tryptophan Dimers
Linked With Aliphatic Chains and Polyamides
Rohtash Kumar, Dinesh Rai, and J. William Lown
VOLUME 14, NUMBER 3
Structure-Activity Relationship
for Alkylating Dipeptide Nitrogen Mustard Derivatives
Joachim Gullbo, Marcus Tullberg, Jon Våbenø, Hans Ehrsson,
Rolf Lewensohn, Peter Nygren, Rolf Larsson, and Kristina Luthman
Shifting Gene Expression
Profiles During Ex Vivo Culture of Renal Tumor Cells: Implications for
Cancer Immunotherapy
Federica Moschella, Richard P. Catanzaro, Brygida Bisikirska, Ihor
S. Sawczuk, Kyriakos P. Papadapoulos, Anthony W. Ferrante, Jr., James M.
McKiernan, Charles S. Hesdorffer, Paul E. Harris, and Antonella Maffei
In Vitro Antitumor Structure-Activity
Relationships of threo/trans/threo mono-Tetrahydrofuranic Acetogenins:
Correlations With Their Inhibition of Mitochondrial Complex I
José R. Tormo, Inmaculada Royo, Teresa Gallardo, M. Carmen
Zafra-Polo, Pilar Hernández, Diego Cortes, and Fernando Peláez
Pleural Mesothelial Cell
(PMC) Defense Mechanisms Against Malignancy
Najmunnisa Nasreen, Kamal A. Mohammed, Kerry Sanders, Joyce Hardwick,
Robert D. Van Horn, P. S. Sriram, Carlos Ramirez-Icaza, Chadi Hage, and
Veena B. Antony
Expression of c-Met Proto-oncogene
in Metastatic Macrophage x Melanoma Fusion Hybrids: Implication of Its
Possible Role in MSH-Induced Motility
Ashok K. Chakraborty, Natalia Kolesnikova, Josane de Freitas Sousa,
Enilza Maria Espreafico, Kamila Chagas Peronni, and John Pawelek
VOLUME 14, NUMBER 2
Frequent Alterations of Smad
Signaling in Human Head and Neck Squamous Cell Carcinomas: A Tissue Microarray
Analysis
Wen Xie, Savita Bharathy, David Kim, Bruce G. Haffty, David L. Rimm,
and Michael Reiss
Effect of 3-Fluorothalidomide
and 3-Methylthalidomide Enantiomers on Tumor Necrosis Factor Production
and Antitumor Responses to the Antivascular Agent 5,6-Dimethylxanthenone-4-Acetic
Acid (DMXAA)
Francisco Chung, Brian D. Palmer, George W. Muller, Hon-Wah Man,
Phillip Kestell, Bruce C. Baguley, and Lai-Ming Ching
Epidermal Growth Factor-Responsive
Laryngeal Squamous Cancer Cell Line Hep2 Is More Sensitive Than Unresponsive
CO-K3 One to Quercetin and Tamoxifen Apoptotic Effects
G. Raspaglio, G. Ferrandina, C. Ferlini, G. Scambia, and F. O. Ranelletti
Reduction of Bladder Cancer
Cell Growth in Response to hCGb CTP37 Vaccinated
Mouse Serum
Stephen A. Butler, Edyta M. Staite, and Ray K. Iles
Characterization of Prostate
Cancer DU145 Cells Expressing the Recombinant Androgen Receptor
Eugenia Scaccianoce, Claudio Festuccia, Donatella Dondi, Vittoria
Guerini, Mauro Bologna, Marcella Motta, and Angelo Poletti
VOLUME 14, NUMBER 1
Modeling the Interaction
of Paclitaxel With b-Tubulin
Michael T. G. Ivery and Tuyet Le
Reductive Metabolism of the
Nitroimidazole-Based Hypoxia-Selective Cytotoxin NLCQ-1 (NSC 709257)
Maria V. Papadopoulou, Ming Ji, Mira K. Rao, and William D. Bloomer
Increased Activity and Expression
of Phospholipase D2 in Human Colorectal Cancer
Hirokazu Oshimoto, Shinichi Okamura, Makoto Yoshida, and Masatomo
Mori
Binding Site(s) on P-Glycoprotein
for a Newly Synthesized Photoaffinity Analog of Agosterol A
Masahiko Mitsuo, Tomohiro Noguchi, Yuichi Nakajima, Shunji Aoki,
Xiao-Qin Ren, Tomoyuki Sumizawa, Misako Haraguchi, Motomasa Kobayashi,
Masanori Baba, Yukihiro Nagata, Shin-ichi Akiyama, and Tatsuhiko Furukawa
Development of a Syngeneic
In Vivo Tumor Model and its Use in Evaluating a Novel P-Glycoprotein Modulator,
PGP-4008
Brian D. Lee, Kevin J. French, Yan Zhuang, and Charles D. Smith