ACUPUNCTURE & ELECTRO-THERAPEUTICS RES., INT. J., Vol. 39, pp. 1-25 , 2014 Copyright ©2014 Cognizant Communication Corp. Printed in the USA. 0360-1293/13 $60.00 + .00 http://dx.doi.org/10.3727/036012914X13966138791109
An Integrated Approach To Individualized Optimal Dose Estimation of Medication By Means of Dosing Adjustment Measures And Bi-Digital O-Ring Test
Dominic P. Lu, D.D.S. Clinical Professor of Oral Medicine, University of Pennsylvania; President, American Society for the Advancement of Anesthesia and Sedation in Dentistry; Attending Teaching Staff, St. Joseph’s Regional Medical Center, Seton Hall University, School of Health and Medical Sciences, Paterson, New Jersey (Correspondence: Tel: (610) 398-1430; Fax (610) 395-8093; E-mail:
Winston I. Lu, R.Ph., Pharm. D. Staff Pharmacist, Providence Hospital, El Paso, TX
(Received: Sep. 18 2013; Accepted with revision: Oct. 10, 2013)
ABSTRACT: Posology concerns science and system of dosage. Conventionally the dosage systems of measurement are the apothecaries’ and metric systems and the dosage calculation for each individual patient has been suggested according to several available methods, namely Clark’s Rule, Fried’s Rule, Young’s Rule, body surface area, or mg/kg, etc. There are many factors affect the availability of a drug to its site of action in the body, and their relation to the time course of drug action and variation in each drug response with or without the other drugs taken simultaneously. The correct dosage requires meticulous and accurate calculation. In busy offices, some may feel the dosage calculation is tedious. This article reviews the conventional methods of dosage calculations and the allergy tests, followed by describing a simple way to determine the proper dosage for each patient by simplifying the Clark’s concept based on the body weight and verify the optimum dosage with Bi-Digital O-Ring Test minimize the adverse drug reactions and to increase safety for drug administration.
Key Words: Posology; Individualized Optimal Dose of Medicine; Dosing Adjustment Measures; Dose-Response Curve; Bi-Digital O-Ring Test; Allergy Tests; Electro-Magnetic Resonance Phenomenon Between 2 Identical Molecules
ACUPUNCTURE & ELECTRO-THERAPEUTICS RES., INT. J., Vol. 39, pp. 27-43, 2014 Copyright ©2014 Cognizant Communication Corp. Printed in the
Unique Aspect of Tibetan Medicine
Abstract: Tibetan medicine is known as the knowledge of healing in the Four Tantras, the main medical text studied by Tibetan doctors. In the 8th century, King Trisong Deutsen (718-785 CE) invited eminent physicians from India, China, Persia, East Turkestan, Mongolia, and Nepal for the First International Medical Symposium in Samye, Tibet and ordered his personal physician Elder Yuthog Yonten Gonpo (708-833 CE), who lived 125 years, and participated in this conference to summarize. By combining all the information available and presented during this symposium, he compiled the Four Tantras. He established the Tanadug medical school at Menlung in Kongpo, Southern Tibet in 763 CE, and worked for the propagation of Tibetan medicine. He is considered an emanation of Medicine Buddha, who is a symbol of mental and physical well being. In his left hand, the Medicine Buddha clasps a begging bowl with long-life nectar, signifying immortality, and in his right, the Chebulic myrobalan (Haritaki), a symbol of good health. Chebulic myrobalan, Belleric myrobalan, and Emblic myrobalan are together called the "3 Fruits" and are common ingredients in Tibetan medicines. Prof. Omura, Y of NY Medical College evaluated these "3 Fruits" and found that one of them available as a "Haritaki," had the highest normal cell telomere increasing effect by optimal dose, with improvement of circulation all over the body, which in turn inhibits cancer activity. He considered Tibetan medicine to be the most advanced medicine in the world before the 19th Century with its well-organized systematic method as described by colorful Tibetan medical paintings by Sangye Gyamtso (1653-1705 CE). During a typical diagnosis, the physician examines the patients’ tongue, radial arteries for pulse beats by the index, middle, and ring fingers of both hands and the urine for features like color, vapor, and bubbles, etc.
Key Words: Elder Yuthog Yonten Gonpo; Medicine Buddha; Chebulic Myrobalan (Haritaki); Telomere; Pulse Examination; Tibetan Urine Examination; Tibetan Medical Diagnostic Methods; Tibetan Medicine.
(Received Dec. 30, 2013; Accepted with revisions; Feb. 16, 2014)